Finally, to determine a common gene target for both Western and Asian cohorts, 450K was used to analyze the paired noncancerous colon tissues and CRC tissues of 26 patients (Table S1), and 8 CpG sites from 6 genes (MSC, ZNF132, PDGFD, BEND5, EHD3, and SOX5) were among the 100 most common ΔAvg_β (βTumor–βNormal) CpG sites of colon cancer in Taiwan (Figure 1B). Here, EHD3 is linked to malignant colon neoplasm.