IFNG and neoplasm: The antitumoral role of IFN has been proven by various studies, for example, murine models showed that IFNα suppresses tumour growth, lack of functional IFNGR (IFNγ receptor) or STAT1 grow tumours faster in presence of carcinogen, and a colon adenocarcinoma model deficient in IFNγ show less tumour regression compared to the control one [9,11,12,53].