TARDBP and amyotrophic lateral sclerosis: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share a common mechanism for mitochondrial toxicity and neurodegeneration caused by protein misfolding and aggregation of mutant superoxide dismutase 1 (SOD1), TAR DNA-binding protein 43 (TDP-43), and RNA-binding protein FUS [123,130].