MDSCs along with MM cell-derived interleukin 10 (IL-10) [7,8,9,10], TGF-β, and IL-6 are also known to impair dendritic cell (DC) maturation and their antigen-presenting function, which further accentuates the immunosuppression [6]. The gene discussed is TGFB1; the disease is Miyoshi myopathy.