In ovarian cancer cells, α-2,6 sialylation of fibroblast growth factor receptor 1 (FGFR1) by ST6GAL1 activated the extracellular signaling-regulated protein kinase 1/2 (ERK1/2) and focal adhesion kinase (FAK) pathway, enhancing cell migration and drug chemoresistance [69]. The gene discussed is FGFR1; the disease is ovarian carcinoma.