Indeed, ST8SIA6-AS1 is upregulated in HCC and can facilitate cell proliferation and resistance to cell apoptosis via sponging miR-4656 and upregulation of HDAC11 expression, suggesting an important role of the ST8SIA6-AS1/miR-4656/HDAC11 axis in regulating HCC cell proliferation [45]. This evidence concerns the gene HDAC11 and hepatocellular carcinoma.