Overexpression of “small nucleolar RNA host gene 16” (SNHG16), also called ncRAN (non-coding RNA expressed in aggressive neuroblastoma) [87], is correlated with bad prognosis in different types of cancer, including bladder cancer [88], breast cancer [89], glioma [90], HCC [91], osteosarcoma [92] and pancreatic cancer [93], being involved in the regulation of apoptosis, migration and proliferation of cancer cells [87]. The gene discussed is SNHG16; the disease is osteosarcoma.