We hold that the present results are also of practical importance, because individuals with higher hs-CRP or CRP levels appeared to be at a dramatically increased risk of reporting a much severe progress of the COVID-19 [148,149]; indeed; higher CRP levels were an independent factor to predict the severity of COVID-19 [149]; given this, we speculate that individuals with OSA and higher hs-CRP and CRP levels might also be at an increased risk to suffer from severe COVID-19. The gene discussed is CRP; the disease is COVID-19.