ALB and neoplasm: Considering the “albumin hitchhiking” phenomenon (the lipid tail at one end of the molecule can bind to serum albumin, which allows the molecule to enter lymph nodes following albumin) when compounds were infused, Irvine et al. synthetized an amph-vaccine (AMP) that consists of a cargo (antigen or adjuvant) linked to a lipophilic albumin-binding tail, which could enter lymph nodes smoothly and induce a 30-fold increase in T cell priming, with better tumor control effect and lower systemic toxicity [69].