When divided into two groups, the median concentrations of preptin were markedly elevated in patients with PTH > 200 pg/mL—1439.5 ng/L ± 2186.75 (median: 695.5) respectively—as compared to the patients without secondary hyperparathyroidism—665 ng/L ± 658 (median: 452 ng/L), respectively (p < 0.05). This evidence concerns the gene PTH and secondary hyperparathyroidism.