In CRC, miR-19a enhances cells invasion, progression and lymph node metastasis by mediating the inhibition of Transglutaminase-2 (TG-2) [50], T-cell intracellular antigen 1 (TIA1) [51] and the inflammatory cytokine tumor necrosis factor α (TNFα) [52]. Here, TNF is linked to colorectal carcinoma.