CALCOCO1 and neoplasm: In addition, primary tumor-derived EV showed expression of proteins involved in intra-Golgi traffic, autophagy and mitophagy, such as periodic tryptophan protein 1 homolog (PWP1), Rab GTPase-activating protein 1 (RABGAP1), TNFAIP3-interacting protein 1 (TNIP1) and calcium-binding and coiled-coil domain-containing protein 1 (CALCOCO1), which interact with GABA Type A Receptor Associated Protein Like 2 and 1 (GABARAPL2 and GABARAPL1) [49].