ATP2A1 and dilated cardiomyopathy: Some evidence of mRNA expression in mammalian cardiomyocytes has been reported [42] and the abnormal protein expression of SERCA1 in cardiomyocytes has been related to dilated cardiomyopathy [41], suggesting that, at least in this condition, the myocardium may be the target of anti-SERCA1 autoantibodies.