The inflammatory mediators such as cytokines and nuclear factor-kappa B (NF-κB) have been extensively studied in inflammatory ocular diseases such as uveitis, retinopathy, and macular edema [22,23,24], and numerous studies on the anti-inflammatory effect of natural flavonoids have been conducted over the past decades [25]. The gene discussed is NFKB1; the disease is macular retinal edema.