As RELM-β is important in lung fibrosis in response to A. fumigatus [94], and LECs [137] and to a lesser degree leukocytes (including eosinophils) [138] produce RELM-β, it is highly likely that additional mechanisms may be activated to induce subepithelial fibrosis in response to fungi. Here, RETNLB is linked to pulmonary fibrosis.