LC3B/TOMM20 (Translocase of Outer Mitochondrial Membrane 20) colocalization in the differentiating myeloid lineage of MDS samples placed mitochondria inside the LC3B+ autophagosomal membrane while LC3B/LAMP1 (Lysosomal Associated Membrane Protein 1) colocalization established autophagy completion with autophagosome–lysosome fusion (Figure 3C–E accordingly, Supplementary Figure S5). The gene discussed is MAP1LC3B; the disease is myelodysplastic syndrome.