Adiponectin levels and the adiponectin-to-creatinine ratio are significantly higher in the urine of SLE patients with renal involvement (renal involvement n = 25, no renal involvement n = 25) [75] and in active LN SLE (n = 33) compared to active non-LN SLE (n = 16), or patients with only LN history (n = 30) [76]. The gene discussed is ADIPOQ; the disease is systemic lupus erythematosus.