ACHE and Alzheimer disease: For example, the Decker group effort noted above also used docking and MD to understand the high affinity of their inhibitors for the human histamine H3 receptors [204] and Samadi et al. docked heterocyclic substituted alkyl and cycloalkyl propargyl amines to AChE, BChE, and monoamine oxidases, which are also closely linked to AD [205].