For the time being, 2 cases have been reported about factor V deficiency, 1 case about fetal vW disease, 1 case of factor VII deficiency, 3 cases of FV Leiden mutation (associated to other polymorphisms), 1 case of protein C deficiency and 1 case of GATA 1 gene mutations. The gene discussed is F5; the disease is congenital factor VII deficiency.