Previous studies conducted by Mukherjee et al. [7] demonstrated that a 70 kDa phosphorylcholine-binding novel antigen (namely FSAg) of the parasite W. bancrofti (the major causative parasite of filariasis in human) is responsible for inducing the inflammatory responses in the host by causing classical macrophage activation through TLR4-NF-κB signaling axis. This evidence concerns the gene NFKB1 and filariasis.