The predictive value of MMP9 was confirmed in a recent cohort study presented by Mechtouff et al. Researchers showed that the highest increase in MMP9 concentration was recorded 6 h after the stroke onset, and augmented level of MMP9 was correlated with infarct growth (OR 3.43 (1.23–9.55); p = 0.02) as well as hemorrhagic transformation (OR 2.48 (1.16–5.27); p = 0.02) [74], thus suggesting that MMP9 may be a useful marker with an ability to exclude patients at high risk of bleeding complications. Here, MMP9 is linked to Stroke.