In a recent publication from our group we demonstrated that the transcriptional co-repressor GCF2 (GC-Binding Factor 2) alias LRRFIP1 (Leucine Rich Repeat (In FLII) Interacting Protein 1) participates in TRIB3 downregulation in cancer cells incubated with rapamycin or its derivatives (rapalogs) [12]. This evidence concerns the gene LRRFIP1 and cancer.