Several findings remained statistically significantly associated with monophasic course of TBE using multivariate testing, including: Age of patients (OR = 1.02; 95% CI: 1.00–1.05), the presence of underlying illness (OR = 1.85; 95% CI: 1.04–3.30), previous vaccination against TBE (OR = 18.45; 95% CI: 1.73–367.10), and duration of neurologic involvement before CSF examination (OR = 1.39; 95% CI: 1.25–1.56) while other covariates (severity of illness, albumin, and IgG quotient, IgG antibody levels against TBEV in serum) did not (Table 2). This evidence concerns the gene ALB and tick-borne encephalitis.