MYC and neoplasm: In addition, cancer cells are characterized by increased ROS levels with respect to normal cells; this is due to their abnormal metabolism, which exploits normal cell machinery in a constitutive way in order to maximize cellular growth and proliferation, to enhance aerobic glycolysis (the so-called “Warburg effect”) [9], and to promote altered expression of pro-tumorigenic networks (as for example, Kras and Myc overexpression [69,70]), as well as the inhibition of tumor suppressors [71].