ALB and neoplasm: In BNCT approaches, covalent conjugation of a maleimide-closo-dodecaborate on albumin lysin (Lys221, Lys413 and Lys431) and cysteine Cys34 residues was reported to selectively accumulate in colon-26 tumor-bearing mice; such a molecule, when used as a boron carrier for BNCT, demonstrated a strong tumor volume reduction at low dose (7.5 mg[B]/kg) [90].