Antibody blockade of the phagocytic receptor MER proto-oncogene tyrosine kinase (MerTK) prevents apoptotic tumor cell clearance by TAMs and mobilizes antitumor immunity via the transport of tumor-derived cyclic GMP-AMP into TAMs and the subsequent activation of STING-dependent type I IFN response [134]. The gene discussed is STING1; the disease is neoplasm.