CFL1 and cancer: Extensive research has broadened our view on how ABPs affect the rate and extent of polymerization through their wide range of functions—maintaining the pool of monomeric actin (profilin), regulating the state of polymerization of actin filaments (ADF/cofilin), regulating actin filament dynamics and capping (gelsolin, villin), severing actin filaments (cofilin, gelsolin), actin filament nucleation (Arp2/3 complex, WASP), binding to the sides of actin filaments (gelsolin, Arp2/3) bundling and crosslinking (fascin, fimbrin) [86], they have been at the forefront of cancer research.