Of the 32,659 age-related methylation sites, two (cg25119261 in HLA-DPB2 and cg05497216 in ANKRD11) were associated with risk of cancer overall (p < 1.5 × 10−6 = 0.05/32,659), and six (overlapping AHSP, SBK1, RASGRP4 and DPEP3 genes) were associated with risk of mature B-cell lymphoma (p < 1.5 × 10−6) (Table 3). This evidence concerns the gene HLA-DPB2 and cancer.