Vijayaraghavan et al. [36] showed, in vitro, on MIN6 mouse insulinoma cells and βlox5 immortalized human beta-cell lines, that the miR-24 directly decreases menin levels via a feedback loop between MEN1-miR-24-menin, similar to that previously shown in parathyroid tissues from MEN1 patients [37]. This evidence concerns the gene MEN1 and pancreatic insulinoma.