ANGPT1 and familial dilated cardiomyopathy: Plasma levels of total NO metabolite (p < 0.0001; Figure 7C), cGMP (p < 0.001; Figure 7D) and Ang (1–7) (p < 0.01; Figure 7E) were significantly suppressed in the DCM mice on LSD injected with L-NAME vs. saline, as measured 4 h post injection, and approaching corresponding levels detected in DCM mice on NSD (Figure 4E and Figure 6D).