The role of VEGF and its receptors in metastasis formation and tumour invasiveness has been claimed in numerous cancers, such as non-small-cell lung cancer, small-cell lung cancer, mesothelioma, hepatocellular carcinoma, cholangiocarcinoma, gallbladder cancer, renal cell carcinoma, glioblastoma, melanoma, osteosarcoma, Ewing sarcoma, chondrosarcoma and pancreatic cancer [12]. The gene discussed is VEGFA; the disease is neoplasm.