These include drugs developed to fight hyperglycemia by interfering in the various events affecting blood glucose, such as insulin secretagogue (sulfonylureas) [2], glucagon-like peptide 1 (GLP-1) analogues, GLP-1 receptor agonists and inhibitors of dipeptidyl peptidase 4 (DPP-4), the GLP-1 inactivating enzyme. This evidence concerns the gene DPP4 and Hyperglycemia.