REN and COVID-19: New evidence, involving analysis of coexpression data in 130,000 transcriptomes of human lung cells, revealed that there are three physiological systems directly involved in the pathogenesis of COVID-19: (I) the kinin-kalicrein system; (II) the renin-system angiotensin; (III) and the coagulation system coexpressed with hACE2-R in alveolar cells [58].