Additionally, it was shown that other pathways are involved in the mediation of CCL2 secretion and TAM recruitment, e.g., upregulation of CtBP1 promoted activation of CCL2 secretion and, as a result, infiltration of TAMs in non-small cell lung cancer (NSCLC) [123]. The gene discussed is CTBP1; the disease is non-small cell lung carcinoma.