Finally, ADC T-DM1 allows a selective delivery of the DM-1 molecule to the HER2-expressing tumor cells, preventing the HER2 homodimerization, and inhibiting the microtubule assembly [77], which induces cell apoptosis [39,40,77], by blocking the AKT/mTOR pathway [40]. The gene discussed is ERBB2; the disease is neoplasm.