Interestingly, Xu et al., 2016 accentuate an increased expression of IL-10 and IL-10 related B cell activation to indicate that IL-10, a potent anti-inflammatory cytokine, plays a crucial role in the pathogenesis of some pathological processes, for example, chronic rhinosinusitis with nasal polyps [37]. The gene discussed is IL10; the disease is nasal cavity polyp.