CD40LG and dengue disease: While a comprehensive review on the performances of various commercially available E-based ELISA kits for both IgM and IgG detection (E-MAC/GAC–ELISA) [42,43] can be found in the literature, relatively fewer studies, summarized in Table 3, have focused on detecting anti-NS1 antibodies for determining dengue serostatus despite its potential utility as diagnostic biomarkers of natural infection.