ncsPCa is defined as a cancer GS of 3 + 3 = 6 involving fewer than two cores at biopsy and <50% of any given core and prostate-specific antigen (PSA) density of <0.15 ng/mL per cm3; it generally has a favorable prognosis, with a high life expectancy at 10 years from diagnosis, and a low risk of biochemical recurrence [4]. This evidence concerns the gene KLK3 and cancer.