In this particular study, the chip-based airway model recapitulated viral infection of asthmatic airway epithelium and neutrophil transepithelial migration, which was greatest when viral infection was combined with IL-13 treatment, while treatment with a CXCR2 antagonist reduced neutrophil diapedesis, concluding that IL-13 plays an inhibitory role in immune response modulation against rhinovirus infection. This evidence concerns the gene CXCR2 and viral infectious disease.