Consistent with the anti-oxidant function of NFE2L2 [49,50,51], tumor cells expressing either L30P or R34P and exposed briefly to H2O2 in vitro recovered from the oxidative stress much more rapidly than either control Δ(90) + YAPS127A tumors or those co-expressing WT NFE2L2 [48]. This evidence concerns the gene NFE2L2 and neoplasm.