NFE2L2 and hemoglobin measurement: Employing the above murine HB model, Wang et al. showed that the enforced co-expression of Δ(90) and YAPS127A, and either of two patient-derived point-mutant forms of NFE2L2 (L30P or R34P [L30P/R34P]), but not WT NFE2L2, generated HBs that grew significantly more rapidly than Group I tumors [20,48].