An additional example is represented by a case study of a 7-year-old patient diagnosed AML with complex karyotype, wild-type FLT3, negative for common chromosomal inversions or translocations, in which Pereira et al. analyzed the immunophenotyping evolution from diagnosis until a third relapse by means of multiparametric flow cytometry [40]. This evidence concerns the gene FLT3 and acute myeloid leukemia.