ALB and Huntington disease: Figure 1 shows serum albumin levels and protein intake (normalized protein catabolism rate: nPCR) of Japanese HD patients from a statistical survey of the Japanese Society of Dialysis Therapy (JSDT) [10]. For example, because the simple standard of low nutrition is a serum albumin level of below 3.5 g/dL, most of the older patients meet this criteria, and hence the possibility of low nutrition in patients is high. In addition, the standard recommended protein intake for HD patients in Japan is 0.9 to 1.2 g/kg/day, but few patients achieve this level (Figure 1).