However, PSMA is overexpressed in the PCa tissue in direct association with the cancer’s aggressiveness, in lymph nodes and bone metastases, and also in other castration-resistant PCa lesions [4,5,6,7], with levels reaching from 100 to 1000 times the values found in non-cancerous prostatic cells [8]. This evidence concerns the gene FOLH1 and posterior cortical atrophy.