ODC1 and neuroblastoma: Disabling ODC1 using the specific inhibitor difluoromethylornithine (DFMO) inhibits neuroblastoma proliferation in vitro as well as in transgenic and patient derived xenograft mouse models of neuroblastoma [10,11,12,13] and based on these findings, clinical trials are being conducted combining DFMO with conventional chemotherapy and/or chemoimmunotherapy in relapsed/refractory neuroblastoma patients (ClinicalTrials.gov Identifier: NCT02030964 and NCT03794349).