In this study, gene-expression profiling of a large panel of early-passage melanoma cell lines [32] identified ROPN1 and ROPN1B as being highly expressed in melanoma tumour samples (ROPN1: 81.8%, ROPN1B: 83.6%), more so than CTAG1 (36.4%). This evidence concerns the gene ROPN1 and melanoma.