Moreover, hypoxia-induced miR-210 expression disturbs melanoma sensitivity to T cell lysis, through the inhibition of genes known to influence this process (PTPN1 (protein tyrosine phosphatase non-receptor type 1), HOXA1 (homeobox A1), TP53I11 (tumor protein P53-inducible protein 11)) (Figure 1) [117,118]. This evidence concerns the gene HOXA1 and melanoma.