We found that plasma IL-6 levels were significantly increased in ischemic stroke patients compared to healthy controls (p = 0.04) (Table 3), and were positively correlated to both plasma TNFR1 (Spearman’s rho = 0.41, p = 0.02) and TNFR2 levels (Spearman’s rho = 0.38, p = 0.03), although not to plasma TNF levels (Spearman’s rho = 0.21, p = 0.24). Here, TNFRSF1B is linked to ischemic stroke.