In this study, we compared blood TNF, TNFR1, TNFR2, CCL2, and CCR2 levels in stroke patients and healthy controls and investigated the association of TNFR1, TNFR2, CCL2, and CCR2 levels to stroke severity, infarct size, and functional outcome at 90 days. The gene discussed is TNFRSF1B; the disease is Stroke.