Despite the trend towards decreased TNFR1+ intermediate monocyte populations in ischemic stroke patients compared to healthy controls (Figure 3f), MFI for TNFR1 on the cells increased in ischemic stroke patients (U = 49, p = 0.05) (Figure 3g), suggesting upregulation of TNFR1 on this cell population. The gene discussed is TNFRSF1A; the disease is ischemic stroke.