The TNFR1+ non-classical monocyte cells [Ctl: 1.00% (0.66–1.49) and IS: 0.23% (0.07–0.39), U = 15, p < 0.001] and the TNFR1+ neutrophil cells [Ctl: 0.28% (0.15–0.57) and IS: 0.05% (0.01–0.19), U = 39.5, p = 0.02] cell populations significantly decreased in ischemic stroke patients (Figure 3f). This evidence concerns the gene TNFRSF1A and ischemic stroke.