In support, similar regulation by GSK-3α but not GSK-3β of the expression of ULBP2/5/6 among other NKG2DL and NKp30L (B7-H6) and target susceptibility to NK cells was observed with K562 cells, a human CML cell line despite the difference in the pattern of ligand expression (Supplementary Figure S9). This evidence concerns the gene NCR3LG1 and chronic myelogenous leukemia, BCR-ABL1 positive.