In order to identify peptides exhibiting a strong tropism towards human hepatoma cells, in a previous work, we elected 12 peptides reported in the literature to bind hepatoma cells, including GB virus A (GBVA10-9) and Plasmodium circumsporozoite protein (CPB), and launched a comparative study of the in vitro internalization by human hepatocytes in primary culture and hepatoma cells of the corresponding biotinylated peptides binding fluorescent streptavidin to form a model bioconjugate [32]. Here, CPB1 is linked to hepatocellular carcinoma.