In another study, Han et al. developed a lipophilic AS1411 aptamer-immunoadjuvant CpG fused sequences (Apt-CpG-DSPE)-modified HDLs for coloading of CpG and DOX (imHDL/Apt-CpG-Dox) for the treatment of lung cancer [137]. Here, LYPLA2P1 is linked to lung cancer.