APOA1 and diabetes mellitus: The nonenzymatic glycation of apoA-I that occurs as a consequence of spontaneous interaction with reactive α-oxoaldehydes generates a diverse array of advanced glycation end-products (AGEs) including Nε-(carboxyethyl) lysine, Nε-(carboxymethyl) lysine and Nω-(carboxymethyl) arginine and is an extensively studied HDL modifications in diabetes [99,100,101].